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Possible reactions include pain or redness at the injection site

Semaglutide also lowers blood pressure, reduces systemic inflammation marked by C-reactive protein, and improves insulin sensitivityall factors that protect against cardiovascular disease

The Phase 2 data did report that retatrutide produced dose-dependent nausea (up to 56% incidence at 12 mg) and injection site reactions, with no adrenal or thyroid adverse events flagged in the primary safety table 1

Personal or family history of medullary thyroid cancer (MTC) : Due to the potential increased risk of MTC linked to Semaglutide GLP-1, people with a personal or family history of MTC should not use this medication

Quick Answer: You can generally drink coffee while taking semaglutide, as there is no direct drug interaction, though coffee may worsen gastrointestinal side effects in some patients